·       Doktorské studium

Univerzita Palackého v Olomouci, Lékařská a stomatologická fakulta, Olomouc

Disertační práce: Vliv ligandů jaderných receptorů PPAR gama na růst a diferenciaci buněčných linií lidského glioblastomu

·       Magisterské studium

Univerzita Pardubice, Fakulta chemicko-technologická, katedra Analýza biologických materiálů, Pardubice

Diplomová práce: Kapilární zónová elektroforéza

·       Bakalářské studium

Univerzita Pardubice, Fakulta chemicko-technologická, katedra klinické biologie a chemie, Pardubice

Bakalářská práce: Biochemické markery osteoporózy

Nicol Straková je autorem 28 publikací s víc jak 485 citacemi a H indexem 13.

1. Besse A, Sedlarikova L, Buechler L, Kraus M, Yang Ch, Strakova N. et al. HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer. British Journal of Cancer 2024, https://doi.org/10.1038/s41416-024-02774-9. IF 6.4, Q1.
2. Hyzdalova M, Prochazkova J, Strakova N, Pencikova K, Strapacova S, Slovackova J, Kajabova S, Libalova H, Topinka J, Kabatkova M, Vondracek J, Mollerup S, Machala M. Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells. Environmental Toxicology and Pharmacology 2024, doi: 10.1016/j.etap.2024.104424. IF 4.2, Q1.
3. Strakova N, Michova H, Shagieva E, Ovesna P, Karpiskova R, Demnerova K. Genotyping of Campylobacter jejuni and prediction tools of its antimicrobial resistance. Folia Microbiologica 2023, 10.1007/s12223-023-01093-5, IF 2.629, Q3.
4. Vrablikova A, Fojtikova M, Hezova R, Simeckova P, Brezani V, Strakova N, Fraiberk M, Kotoucek J, Masek J, Psikal I. UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine. Scientific Reports 2023, 10.1038/s41598-023-46791-9. IF 4.996, Q1.
5. Korena K, Krzyzankova M, Florianova M, Karasova D, Babak V, Strakova N, Juricova H. Microbial succession in the cheese ripening process—competition of the starter cultures and the microbiota of the cheese plant environment. Microorganisms 2023, 11, 1735. 10.3390/ microorganisms11071735, IF 4.926, Q2.
6. Strakova N, Shagieva E, Ovesna P, Korena K, Michova H, Demnerova K, Koláčková I, Karpiskova R. The effect of environmental conditions on the occurrence of Campylobacter jejuni and Campylobacter coli in wastewater and surface waters. Journal of Applied Microbiology 2022, IF 3.066, Q2.
7. Strharsky, T; Pindjakova D, Kos J, Vrablova L, Michnova H, Hosek J, Strakova N, Lelakova V, Leva L, Kavanova L, Oravec M, Cizek A, Jampilek J. Study of Biological Activities and ADMET-Related Properties of Novel Chlorinated N-arylcinnamamides. International journal of molecular sciences IF 6.208, Q1.
8. Sperling D, Isaka N, Karembe H, Vanhara J, Vinduska J, Strakova N, Kalova A, Kolackova I, Karpiskova R. Effect of the vaccination agains Shiga toxin 2e in a farm with history of oedema disease, caused by atypical Escherichia coli producing Shiga toxin (STEC). Veterinarni medicina IF 0.746, Q4.
9. Strakova N, Korena K, Gelbicova T, Kulich P, Karpiskova R. A rapid culture method for the detection of Campylobacter from water environment. International Journal of Environmental Research and Public Health 2021, 18, 6098. 10.3390/ijerph18116098. IF 2,849, Q1.
10. Strakova N, Korena K, Karpiskova R. Klebsiella pneumoniae producing bacterial toxin colibactin as a risk of colorectal cancer development – A systematic review. Toxicon 2021, 197. 10.1016/j.toxicon.2021.04.007. IF 2.201, Q3. 37 citations.
11. Hofmanová J, Slavík J, Ciganek M, Ovesná P, Tylichová Z, Karasová M, Zapletal O, Straková N, Procházková J, Bouchal J, Kolář Z, Ehrmann J, Levková M, Hušková Z, Skalický P, Kozubík A, Machala M, Vondráček J. Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells. International Journal of Molecular Sciences 2021, 22, 6650. https://doi.org/10.3390/ ijms22136650. IF 4.556, Q1.
12. Slovackova J, Slavík J, Kulich P, Vecera J, Kovac O, Paculova H, Strakova N, Fedr R, Silva JP, Carvalho F, Machala M, Prochazkova J. Polychlorinated environmental toxicants affect sphingolipid metabolism during neurogenesis in vitro. Toxicology 2021. IF 4.571, Q1.
13. Machala M, Slavik J, Kovac O, Prochazkova J, Pencikova K, Parenicova M, Strakova N, Kotoucek J, Kulich P, Mollerup S, Vondracek J, Hyzdalova M. Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes. International Journal of Molecular Sciences, 2021, 10.3390/ijms22179195. IF 6.208, Q1.
14. Gelbicova T, Florianova M, Hluchanova L, Kalova A, Korena K, Strakova N, Karpiskova R. Comparative Analysis of Genetic Determinants Encoding Cadmium, Arsenic, and Benzalkonium Chloride Resistance in Listeria monocytogenes of Human, Food, and Environmental Origin. Frontiers in Microbiology 2021, 11:599882. 10.3389/fmicb.2020.599882.  IF 4.236, Q1.
15. Gelbicova T, Korena K, Pospisilova L, Strakova N, Karpiskova R. Dissemination and characteristics of Klebsiella spp. at the processed cheese plant. Czech J of Food Science 2021, 39 (2), 113-121. 10.17221/232/2020-CJFS. IF 0.934, Q4.
16. Shagieva E, Teren M, Michova H, Strakova N, Karpiskova R, Demnerova K. Adhesion, biofilm formation, and luxS sequencing of Campylobacter jejuni isolated from water in the Czech Republic. Frontiers in Cellular and Infection Microbiology 10.3389/fcimb.2020.596613. IF 4.123, Q2.
17. Procházková J, Slavík J, Bouchal J, Levková M, Hušková Z, Ehrmann J, Ovesná P, Kolář Z, Skalický P, Straková N, Zapletal O, Kozubík A, Hofmanová J, Vondráček J, Machala M. Specific Alterations of Sphingolipid Metabolism Identified in EpCAM-positive Cells Isolated From Human Colon Tumors. Biochimica et Biophysica Acta – Molecular and cellular biology of lipids 2020, 158742. 1016/j.bbalip.2020.158742. IF 4.402, Q1.
18. Hofmanova J, Slavik J, Ovesna P, Tylichova Z, Dusek L, Strakova N, Vaculova A, Ciganek M, Kala Z, Jira M, Penka I, Kyclova J, Kolar Z, Kozubik A, Machala M, Vondracek J. Phospholipid profiling enables to discriminate tumor- and non-tumor-derived human colon epithelial cells: Phospholipidome similarities and differences in colon cancer cell lines and in patient-derived cell samples. PLoS One 2020, e0228010. 1371/journal.pone.0228010. IF 2.776, Q2.
19. Tylichová Z, Slavík J, Ciganek M, Ovesná P, Krčmář P, Straková N, Machala M, Kozubík A, Hofmanová J, Vondráček J. Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells. Journal of Cellular Biochemistry 2018, 10.1002/jcb.26641. IF 2.959, Q2.
20. Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vašíčková K, Kolářová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Ešner M, Jaroš J, Hampl A, Krejčí L, Paruch K, Souček K. Synthesis and profiling of a novel potent selective inhibitor of CHK1 kinase possessing unusual N-trifluoromethylpyrazole pharmacophore resistant to metabolic N-dealkylation. Molecular Cancer Therapeutics 2017, 16 (9), 1831-1842. 10.1158/1535-7163.MCT-17-0018. IF 5.365, Q1.
21. Tylichová Z, Straková N, Vondráček J, Vaculová A, Kozubík A, Hofmanová J. Activation of autophagy and PPARgamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: the role of cell differentiation. Journal of nutritional biochemistry 2017 39:145-155. 1016/j.jnutbio.2016.09.006. IF 4.414, Q1. 36 citations.
22. Hofmanová J, Slavík J, Ovesná P, Tylichová Z, Vondráček J, Straková N, Vaculová A, Ciganek M, Kozubík A, Knopfová L, Šmarda J, Machala M. Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities. European journal of nutrition 2016 Mar 16, doi:10.1007/s00394-016-1196-y. IF 4.423, Q1.
23. Slabáková E, Kharaishvili G, Smějová M, Pernicová Z, Suchánková T, Remšík J, Lerch S, Straková N, Bouchal J, Král M, Culig Z, Kozubík A, Souček K. Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells. Oncotarget 2015, 6 (34):36156-71. doi: 10.18632/oncotarget.5392. IF 5.168, Q1.
24. Hofmanová J, Straková N, Hyršlová A, Tylichová Z, Šafaříková B, Skender B, Kozubík A. Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer. Mediators of inflammation 2014, 848632. 1155/2014/848632. IF 3.263, Q2. 43 citations.
25. Fedr R, Pernicová Z, Slabáková E, Straková N, Bouchal J, Grepl M, Kozubík A, Souček K. Automatic cell cloning assay for determining the clonogenic capacity of cancer and cancer stem-like cells. Cytometry A 2013, 83 (5), 472-82. 10.1002/cyto.a.22273. IF 3.066,
26. Ehrmann J, Straková N, Vrzalíková K, Hezova R, Kolář Z. Expression of STATs and their inhibitors SOCS and PIAS in brain tumors. In vitro and in vivo study. Neoplasma 2008, 55 (6), 482-487. PMID: 18999875, IF 1.179, Q3.
27. Straková N, Ehrmann J, Bartoš J, Malíková J, Doležel J, Kolář Z. Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors. Neoplasma 2005, 52 (2), 126-136. PMDI: IF 0.731, Q3. 62 citations.
28. Straková N, Ehrmann J, Džubák P, Bouchal J, Kolář Z. The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines. Journal of pharmacology and experimental therapeutics 2004, 309 (3), 1239-1247. 1124/jpet.103.063438. IF 4.335, Q1. 58 citations.